Monday, December 30, 2019

Importance Of The Reproductive Neurendocrine Prochans In...

The evidence in the literature suggests that the reproductive neuroendocrine axis is centrally regulated through inputs from kisspeptin-expressing neurons to GNRH-expressing neurons, which afterward regulate the release of LH and FSH from the anterior pituitary [Aki et al., 2015]. Kisspeptin primarily participates in the regulator of the reproductive axis performed its capability to operate upon, and evoke GNRH neurons, which have been shown to express GPR54 [d’Anglemont and Colledge, 2010]. Vaccination with kisspeptin DNA vaccine results in the production of anti-kisspeptin antibodies that suppress GNRH and block the synthesis of testicular steroids and reduce kisspeptin concentration level in the blood. The result of the current study†¦show more content†¦These findings suggested that P234 vaccination modulated the median eminence kisspeptin-kiss1r signaling take part in the kisspeptin-stimulated testosterone release and may not passed the blood-brain barrier. Furth ermore, plasma kisspeptin, LH, and FSH levels in controls are significantly increased relative to animals with hypogonadotropic hypogonadism [Kotani et al., 2014]. Moreover, kisspeptin-54 concentration level in the blood of control group was significantly higher than treatment group [Messager et al., 2005]. Further, peptide 234 suppressed the synthesis of GNRH in both prepubertal and pubertal monkeys [Guerriero et al., 2012] and administration of peptide 234 delays the onset of puberty in rodents [Pineda et al., 2010]. Beale et al., [2014] reported that the maintenance of ARC-kisspeptin concentration is crucial for normal LH pulsatile release and estrous cycle and decrease the LH pulse frequency. Administration of kisspeptin antagonist reduced LH secretory response to intracervical vaccine immunization of kisspeptin. This cumulative evidence indicates that the kisspeptin antagonist inhibited GNRH neuron and would reduce hypothalamus GNRH secretion in vivo. Hypothalamus, pituitary, and testicular tissues were collected to quantify mRNA levels using qPCR. Accordingly, kisspeptin, Kiss1r, and GNRH mRNA concentrations in the hypothalamus were significantly lower in the treatment group than in the control group (P

Sunday, December 22, 2019

My Jewish Identity in Conflict Essay - 1397 Words

My Jewish Identity in Conflict When I think of my cultural identity, my religion--Judaism--comes to mind first and foremost. When I think of my Jewish identity in conflict, racism (in my case anti-Semitism) is the obvious factor. But to fully define my conflict with my religious identity, I cannot only write from personal experiences with racism. I must also include the anti-Semitism that my forefathers have endured, from the beginning of time up to today, ranging from the Spanish Inquisition to the Holocaust, from the massacre at the Munich Olympics to Iraqs actions in the Persian Gulf War. From direct racism and intended hatred to subtle racism in the form of jokes and passing comments, anti-Semitism has played a big part in my†¦show more content†¦Anti-Semitism continues around the world today. In the recent Persian Gulf War, Saddam Hussein bombed Israel in several areas even though Israel was not involved in any part of the war. Just a few days ago, on October 26, six Israeli soldiers were killed inst antly when a bomb in their jeep, planted by Iranian terrorists, exploded. Obviously, I have never gone through anything close to what the aforementioned have, but I have endured racism personally. In a high school junior varsity basketball game my sophomore year, our team traveled to a nearby high school. At the very end of the game (it was a blowout in our favor, and there was not much of a crowd), I was dribbling near the opposing teams bench when all of a sudden, one of their players on the bench yelled, Go home, you fucking Jew! I couldnt believe it. I just stopped playing and stared at him, while my teammates waited for me to do something with the ball. I had never heard anything like that directed at me before. At first, I was in what might best be called shock, and then, after time had expired, I walked over to our bench and my shock turned to anger. I didnt know what to do. I didnt confront him physically or verbally, because I feared my anger might get the best of me. That wouldnt bode well for me, since Im not exactly Muhammed Ali. In the end, I just went into the locker room without saying a word. I never really have put this behind me. Im not saying that I amShow MoreRelated The Me Nobody Knows Essay1494 Words   |  6 PagesThe Me Nobody Knows Throughout most of my life I have often confronted myself with the question of self-identity. My past is inundated with people I have been: the quiet, reserved child, the intellectual, arrogant adolescent, and recently the cool, collected young woman. My once alternating identity was a product of the tendency we all have to accommodate others, often sacrificing part of ourselves in the process. The perception others have of becomes most important and the thoughts, feelingsRead MoreAnalysis of The Jewbird Essay1017 Words   |  5 Pagescharacters, and conflict to show the issues surrounding personal identity and assimilation among American Jews. The dominant themes in this short story are the human capacity to foster hatred towards those who are different in the form of anti-Semitism, and the conflict that exists between Jews who have assimilated into American culture and those who have not relinquished their Jewish identity. 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Friedman uses the social sciences to analysis the situation that he observed when he was in Beirut writing for The New York Times. Being that Friedman is Jewish I rode off the book as a one-sided view of the happenings in the Middle East. What I found was quite the opposite; Friedman took a neutral position. Analyzing the situation in the Middle East is by no means an easy thing. There have of course beenRead MoreReb Tevyes Tradition, Family, and Religion over Time1394 Words   |  6 PagesTevye speaks directly to the camera. As a viewer, I felt that Tevye was speaking what he believed to be the truth about his family and his traditions. This gave me the opportunity to make my own judgments and decisions about what Tevye’s priorities are, without the possibility of someone else’s opinions skewing my own. I think this reflects a huge generational change between when the book was published and when the movie came out. 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Saturday, December 14, 2019

Twilight Movie vs Book Free Essays

The Twilight saga is a fantasy book that became even more popular with the movie that came out two years after the book. Twilight is about a teenage girl that brings danger to her life by falling in love with an immortal vampire. The book is written by Stephanie Meyer who has written 3 more books to the series. We will write a custom essay sample on Twilight: Movie vs Book or any similar topic only for you Order Now Even thought that the movie â€Å"Twilight† was based on the book it had a lot of differences and there were a lot of missing parts. One of the biggest differences is that the book is written from Bella’s thoughts; it is really she who narrates the situations she is in. The reader gets to be Bella in a way and you find out everything she thinks and feels about Edward. Although in the movie reflects on both Bella and Edward, by watching the movie you don’t get the same feeling as in the book. If there are some private thoughts of Bella that the viewer must know about, you get them in the context of the story; it feels almost like Bella is writing a diary. Another important difference is how Bella finds out that Edward is a vampire. In the book, the school they are going in is having a dance and because Bella is not really that in to dancing she and Edward decide to go to Seattle, but the don’t even go to Seattle instead Edward takes Bella to the meadow and tells her what he is and he reveals himself in the sunlight so that she can see that he is sparkling in the sunlight. In the movie they are in front of their school preparing to go to class and Edward decides to go to the nearby forest, Bella went after him and she confessed that she knows what he is, Edward was surprised and he tries to scare her by showing himself in to the sunlight so that she can see that he is sparkling. However the book and the movie have a lot of similarities as well. The family dynamics are described very well. In the book Bella’s mother Rene is very eccentric and she cares a lot about Bella, even though she does not get more than a few minutes in the movie, you can easily see her personality. It is the same with Bella’s father Charlie, he did not spend much time with Bella when she was little and the awkwardness between them is described well in the book and in the movie. Altogether both the book and the movie follow the same storyline. As I mentioned earlier the movie is based on the book twilight and it is hard to miss that, they have the same method and all the important characters. I would recommend to read the book first and then watching the movie because the small differences in the movie are significant as of course that depends from the viewers. How to cite Twilight: Movie vs Book, Essay examples

Friday, December 6, 2019

Character Sketch free essay sample

Who would think that an old fragile woman would have such a feisty personality in her childhood? Yes, we are talking about the one and only Kim Cowley from the play script â€Å"Brother in the Land† During her time of youth, Kim was what every girl would wish to be. Throughout the play script, she has been described very determined, fearless and ambitious. The true characteristics of a great leader. When Kim was first introduced into the story, she was shown very wild and selfish. When her ‘so-called’ friends tried to steal her bag of food after the tragic nuclear attack, she was ruthless and attempted to kill one of them, and would have finished the job if Danny had not stopped her. She does not regret her actions at all, as after the fight for food ended, she said â€Å"He wouldn’t have thought twice about doing (killing) me in. Then simply tell what happened as you spent time together. From time to time, describe the persons gestures or facial expressions. It is important to put words into the persons mouth in direct quotations. As you work on this paper, you should decide what kind of emotional reaction you want the reader to have in relationship to this person. What kind of details can you select to create that emotional reaction? Avoid making broad characterizing statements; instead, let the details you give suggest general characteristics. Let the reader draw her own conclusions. Example of a Character Sketch Grandma Atkinson (Courtesy of the Northern Illinois University Writing Across the Curriculum Program) We pulled into the gravel driveway and nudged the front bumper of the 1953 Chevy up to the left garage door. Climbing out of the car, we walked across the driveway to the homemade brick sidewalk, past the patch of blooming, orange day lilies, around the corner of the large, white, frame house to the green screen door. As we opened the squeaky door, we passed from the bright sun of a mid-summer day in Bertrand, Nebraska, into the back porch of Grandpa and Grandmas house. Our eyes needed to adjust to the darkness, but we could make out the coveralls hanging on the far wall, a bushel basket in one corner, and a pail with garden hand tools against another wall. We stepped up a step into the kitchen, a window to our left and old, white wooden cupboards with counters lining the two walls to our left. At the end of the isle between the two sets of cupboards was a gas stove on one side, and a squat-looking refrigerator with rounded corners across the isle. A coffee pot sat on the stove, and I could smell the rancid aroma of over-cooked coffee. Passing on through the narrow kitchen, we stepped into the spacious dining room, dominated by a large round, wooden table. Anyone home? You here, Mom? My mother called out. About the same time, Grandma appeared in the door of her bedroom across the room from where we stood. Glory, be! Look whose here. Grandma said, wiping her wrinkled hands on her faded apron. She shuffled slightly as though she were about to step on into the dining room, but before she could make her move, my mother had dashed across the room and was giving her a hug. Dad and I followed sheepishly across the room, knowing that the mandatory hug was about to happen. When it was my turn, I could feel the soft, loose flesh of Grandmas sagging arms as she hugged me close and placed a wet smack on my turned cheek. Grandmas lavender-scented perfume obliterated the faint whiff of mothballs that permeated Grandma and Grandpas house. She was a small woman, not much taller than me, much shorter than my mother. She had pure white hair that she always wore up in an old fashioned bun. Here hair was actually quite long. I know because every night she would comb it out, leaning forward and combing the hair from the back of her head down to the floor in long strokes that looked like they tired her sagging arms. Grandma always wore dresses that hung to mid calve, usually buttoned up the front, covered by one of her many faded aprons. It wasnt long before we were all sitting around the large, round wooden table in the dining room, looking out through the large windows, draped in white sheers, to the large side yard where my favorite apple tree stood. It was time for the 4:00 coffee break. Grandpa had come in from the garden where he had been pruning tomato plants, their pungent odor still clinging to his hands. Grandma had made a pot of fresh coffee, adding an egg white to the boiling brew at the last minute to clarify the coffee. Even so, we would all find grounds in the bottom of our cups. Even though I was only seven years old, I had been drinking coffee at Grandmas house for as long as I could remember. Each of us had a coffee cup with a flower pattern, which sat on a matching saucer. A plate of rusks, dried toast pieces, was being circulated for dipping. There was also a tin with saltine crackers. I took two squares, and, when the creamery butter .